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Six metabolites have been identified: 2-ethylisonicotinamide, carbonyl-dihydropyridine, thiocarbonyl-dihydropyridine, S-oxocarbamoyl dihydropyridine, 2-ethylthioisonicotinamide, and ethionamide sulfoxide, the latter having significant antimycobacterial activity (Henderson et al., 2008

Under the countrys pharmaceutical affairs law, all nicotine-containing e-liquids are classified as drugs, with liquid-inhaling devices (i.e