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Nt-acetylation can regulate the subcellular localization of proteins, protein stability, and protein-protein interactions 4

Research shows that 420 to 600 mg of silymarin per day may provide beneficial effects in patients affected with liver disease or abnormal liver function

10.1038/nn2004 152 RothmanD

Potential Side Effects and Considerations While 1500 mg is generally safe, taking high doses of any supplement can sometimes lead to minor side effects