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Description

Under hypoxic conditions, ULK1 phosphorylates the mitochondrial outer membrane protein FUNDC1, enhancing its binding to LC3 and thereby initiating receptor-mediated mitophagy to remove damaged mitochondria

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[DOI] [PMC free article] [PubMed] [Google Scholar] 20.Yang XP, Reckelhoff JF

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Upregulation of cystathionine-beta-synthase in colonic epithelia reprograms metabolism and promotes carcinogenesis

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When they come into play, they switch on the pituitary gland to release luteinizing hormone (LH), and thats the green light for the testes to crank up testosterone

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Cerebral derailment following myocardial infarct: mechanisms and effects of the signaling from the ischemic heart to brain

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Inhibition of mTORC2 reduces the activity of PKC/, which then disrupts the actin cytoskeleton, decreases the number of Atg16L1 + vesicles, and clathrin-dependent endocytosis

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