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Diabetes (2018) 67(4):74554

XYL, GXW, and CRK wrote the manuscript

Iron depletion and repletion with ferrous sulfate or electrolytic iron modifies the composition and metabolic activity of the gut microbiota in rats

Maximum decline from baseline in ALT was 11.0 U/L in 3 mg, 15.5 U/L in 6 mg FXR314 versus 8.1 U/L in placebo

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Along with the recognition of such patients, elucidation of the molecular mechanisms of steroid resistance is equally important, so that administration of a high dosage of steroids, and the consequent adverse effects, can be avoided