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UCHL1's activity is essential for the removal of misfolded or damaged proteins, preventing protein aggregation that can lead to cellular dysfunction and disease

CPT1A to reduce fatty acid oxidation-driven neuroinflammation for neurobehavioral recovery CPT1A, the rate-limiting enzyme in mitochondrial FAO, is a pivotal therapeutic target in ischemic stroke due to its role in amplifying neuroinflammation

Y.FujiwaraT.AwazuharaM.KimuraT.NojiM.SaitoK

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Briefly, 5000 A549 cells were seeded in eight replicates per condition, then treated with either 1, 5, 10 M KA or vehicle control (DMSO)