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Our typical stem-cell patient has Osteoarthritis (hip dysplasia, degenerative joint disease, calcifications, common degeneration, and inflammation) Soft tissue injuries (cruciate injuries, tears, ruptures, inflammation), or Needs accelerated healing of fractures

Spatial transcriptomics of archived FFPE biopsies identifies pre-treatment signatures associated with VDZ response and non-response To examine tissue level differences between VDZ responders (VDZ-R) and non-responders (VDZ-NR), we retrieved longitudinal archived FFPE biopsies before and after therapy and performed 1000-plex CosMx spatial transcriptomics (Fig