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After treating HaCaT with 580 M CuCl 2 or Cu(OAc) 2 , the expression of IL1A, IL8, HSPA1A and FOSL1 were significantly higher than that in the control group and ranged from a 844 fold change

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In fruit flies and rats, some studies observed a reduction in age-related mortality indices, and in specific mouse strains predisposed to cardiovascular and oncologic conditions, trends toward longer survival were reported under defined conditions