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Similarly, CCMV, P22, and Q VLPs have been extensively employed to complex nucleic acids for vaccine development by leveraging their positively charged interior surfaces (Comas-Garcia et al., 2012

Eliseev IE, Yudenko AN, Vysochinskaya VV, Svirina AA, Evstratyeva AV, Drozhzhachih MS, Krendeleva EA, Vladimirova AK, Nemankin TA, Ekimova VM, Ulitin AB, Lomovskaya MI, Yakovlev PA, Bukatin AS, Knyazev NA, Moiseenko FV, Chakchir OB (2018) Crystal structures of a llama VHH antibody BCD090-M2 targeting human ErbB3 receptor

It is therefore reasonable to assume that PD could be modulated by differentially targeting the three predominant sirtuins (SIRT1, 2, and 3), which are of primary relevance to mitochondrial dysfunction in PD (Lin et al., 2018)

The harmful byproducts are either recycled or removed from the body

Zhang Y, Huang J, Fu D, et al

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