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doi: 10.1038/nm.3563 30 BesbesA.Le GoffS.AntunesA.TerradeA.HongE.GiorginiD.et al

Image description: Infographic provides overdose information about the following substances: Opiates Unresponsive or unconscious, depressed or nonexistent breathing, snoring/gurgling sounds, cold/clammy skin, cyanotic skin discoloration Methamphetamines Agitation, chest pain, arrythmia, cardiac arrest, stroke, kidney damage, abdominal pain, coma Gabapentin Drowsiness, muscle weakness, sedation, drooping eyelids (Rarely fatal alone) Benzodiazepines Excessive sedation, amnesia, respiratory depression, coma (Rarely fatal alone) Isotonitazene Similar to other opiates, but 10x more potent than fentanyl-requires significantly more Narcan doses

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Acute inflammation is a necessary signal for immune cells to clear debris and initiate repair