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Materials and Methods Housing Mice at Different Temperatures Female, 4-week old C57BL/6J mice were obtained from the Chongqing Medicine University, Department of Laboratory Animal Resources

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Raf-1 GST RBD 1149 was a gift from Channing Der (Addgene plasmid 13338) (65)

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elegans , murine, and human cell models each provide unique mechanistic insights, we acknowledge that differences in physiology and gene regulation may limit direct translation of the findings

Due to the small size of QDs and thus high surface-to-volume ratio as well as the photoluminescence (PL) mechanism itself [5], any subtle interactions between surface atoms and the surrounding molecules can significantly influence QDs photoluminescence characteristics such as quenching/enhancement of emission intensity, spectral shifts, and change in the PL decay time, which make them one of the most advantageous nanoparticles for chemical sensing