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First of all, using descriptive and accurate terms helps clinicians and patients better understand the pathophysiology caused by stress and the stress response system

All methods used a Waters ACQUITY ultra-performance liquid chromatography (UPLC) and a Thermo Scientific Q-Exactive high resolution/accurate mass spectrometer interfaced with a heated electrospray ionization (HESI-II) source and Orbitrap mass analyzer operated at 35,000 mass resolution

Eur J Neurosci 39 : 16711681

Excretion: Metabolites are excreted primarily through the kidneys

Proc Natl Acad Sci USA 4, 370373 (1918)

So let me give you a clear, honest, evidence-based look at what we actually know, what remains uncertain, and what I tell my patients when they ask about it