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Given that nearly all first use of cigarettes occurs by 18 to 26 years of age, efforts to reduce smoking initiation should continue to target adolescents and younger adults

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Patients treated concomitantly with ZYBAN and such drugs may require increased doses of the drug [see Clinical Pharmacology (12.3)]

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Its well known that traditional cigarettes can increase the risk of type two diabetes and related complications, but researchers are still analyzing the potential relationship between e-cigarettes and the disease