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Since, we all get one copy of the MTHFR gene from each parent, a person could have any one of the following combinations as well as the problems that go with it: Interpreting 23andme results And its very rare, but some folks can even have 3 mutations (a double mutation in one gene and a single mutation on the other) or conceivably 4 mutations (though Ive not heard of any specific case of this in real life) if they have: Treatment Most cases of MTHFR deficiency are treated with folate supplementation (specifically methylfolate, the most active form of folate in the body), methyl-B12 supplementation, P5P supplementation, and dietary changes

J Clin Pharm Ther 25:325332 Thummel KE, Slattery JT, Ro H, Chien JY, Nelson SD, Lown KE et al (2000) Ethanol and production of the hepatotoxic metabolite of acetaminophen in healthy adults

If purging seems excessive or extends beyond eight weeks, the copper peptide troubleshooting guide provides additional strategies

10.3390/ijms23094558 7 CalientoR.SarmentoD