can melanotan 2 cause vitiligo

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10.1002/cam4.5382 37 PlikusM

72 Previous Study has shown that SAH can reduce the expression of DNA methyltransferase DNMT1 protein, lead to demethylation of the CpG islands in the NF-B gene promoter region, and increase NF-B expression, trigger the expression of pro-inflammatory senescence-associated secretory phenotype (SASP) factors, and thus induce cellular senescence in rat aortic smooth muscle cells