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In the phase 1/2 trial, alpelisib (a PI3K inhibitor) plus nab-paclitaxel was well tolerated and showed encouraging efficacy, especially in patients with metastatic PIK3CA -mutated HER2 breast cancer, despite that TNBC has lower efficacy than HR+/HER2 patients

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Regulation of plasma lipid profile by Lactobacillus fermentum (probiotic strain ME-3 DSM14241) in a randomised controlled trial of clinically healthy adults

inhibiting lipid peroxidation and ferroptosis to maintain redox balance (115)

5 Conclusion In this study, we successfully isolated and identified A

The advantages of MOTS-c as a therapy option come from its ability to improve endurance, support muscular recovery, and modulate metabolic response, all of which result in increased athletic performance and decreased muscle loss and weakness brought on by aging