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Additionally, many alkaloids trigger apoptosis in cancer cells by activating intrinsic pathways that promote the release of cytochrome c from mitochondria

While in vitro studies and animal models have provided positive indications, it is crucial to validate these findings in human subjects to establish the relevance and applicability of A1AT augmentation treatment

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doi:10.1183/20734735.000618 Neighbors CLP, Noller MW, Song SA, et al