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2a) It is important to note that there is also evidence to the contrary that suggests G6PD-d may exert a vasoprotective effect by preventing pathogenic VSMC proliferation, limiting vasoconstriction, and protecting against angiotensin II-induced hypertension 45,46

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Additionally, total carotenoid and -carotene concentrations have been found to be negatively correlated with temporal lobe atrophy, indicating a potential protective effect against age-related neurodegeneration (26)

10.1016/j.jot.2024.10.005 5 CaoJ.ChenX.ChenL.LuY.WuY.DengA.et al (2025)