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Site-directed mutagenesis was performed using the QuickChange II kit and specific primers (listed in Table S2) to create five different LMNA variants, and the mutant sites were confirmed by sequencing before proceeding with the LR reaction

Eher aus totaler Verzweiflung als als aus berzeugung

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Notably, LMNA (WT) fish did not exhibit significantly different muscle endurance compared to the AB(WT) fish (Fig

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Feline DM and HC can be treated in various ways including medically (trilostane), surgically (adrenalectomy, hypophysectomy) or with radiotherapy, depending on the type of HC and caregiver preference