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Cutaneous adverse reactions to anti-PD-1 treatment-a systematic review

A significant obstacle to achieving this is the susceptibility of probiotics to a confluence of hostile conditions, including gastric acidity, bile salts, temperature variations, and antimicrobial factors such as hydrogen peroxide, which can severely diminish their viability and functionality (273)

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The recognition that glutathione exists in two forms reduced GSH and oxidised GSSG and that the two are interconverted by the enzymes glutathione peroxidase and glutathione reductase, was developed across the mid-twentieth century