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5 Conclusion In conclusion, data from this study provide important insight into nicotine delivery, pharmacokinetics and subjective effects during the use of a range of NPs in current smokers who also use snus, and demonstrate that while the C max and AUC values from these products match or exceed those of a combustible cigarette during smoking, T max is slower

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BenowitzNLPipeAWestRHaysJTTonstadSMcRaeTet alCardiovascular safety of varenicline, bupropion, and nicotine patch in smokers a randomized clinical trial