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In aged animal models, growth hormone secretion is typically reduced by 50-70% compared to young adult levels, contributing to many of the physiological changes associated with aging including alterations in muscle mass, increased adiposity, reduced bone density, modified immune parameters, and decreased tissue repair capacity

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Neutrophil elastase inhibitor suppresses oxidative stress in obese asthmatic rats by activating Keap1/Nrf2 signaling pathway

Am J Psychiatry 1983

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