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( 3.1.2 Active immune recognition interferes with innate immune responses MP can synthesize capsular polysaccharides (CPS) similar to those on host cell surfaces, forming a physical barrier that conceals its highly immunogenic LAMPs and lipopeptides from TLR recognition ( in vitro to induce IL-10 secretion and inhibit dendritic cell maturation via the DC-SIGN pathway (65)

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Mingorance C, Rodriguez-Rodriguez R, Justo ML, Herrera MD, de Sotomayor MA

It was found that this asymmetric structure facilitates the separation of the desired bispecific compound from unwanted immunoglobulin chain combinations, as the presence of an immunoglobulin light chain in only one half of the bispecific molecule provides for a facile way of separation