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Excessive synaptic pruning by microglial cells (MCs), reduced myelination and energy supply of axons by oligodendrocytes (OLs), and impaired synaptic plasticity, synaptic glutamate recycling and neuronal energy supply due to astrocyte (AC) dysfunction may lead to an excitatory-inhibitory imbalance and increased vulnerability (e.g

4c,d and Extended data Table 3)

GHK-CU dosing by goal Different objectives require different approaches

Anyone considering the compound should understand these realities

Gels 11:7 Rando HM, Lordan R, Kolla L, Sell E, Lee AJ, Wellhausen N, Naik A, Kamil JP, Consortium C-R, Gitter A (2023) The coming of age of nucleic acid vaccines during COVID-19

Psychiatry 115 KeszyckiR.RodriguezG.LocciA.OrellanaH.HaupfearI.DominguezS.et al (2021)