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Abstract The increasing incidence of oral malignancies, coupled with the limitations of conventional treatments such as toxicity and drug resistance, has driven the exploration of novel therapeutic approaches

An example for this latter mechanism is Trx oxidation by the Prx dimer (as in Fig

doi: 10.1183/13993003.00791-2016 242 WeinbergE

Niu X, Chen L, Li Y, Hu Z, He F

In 2025, the oncology field saw a notable increase in smallmolecule approvals and a greater reliance on response rate as the primary efficacy endpoint for accelerated and regular approvals