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11, 1964 when the Surgeon General published the report declaring tobacco carcinogenic, more than 40 percent of American adults smoked

These factors further demonstrate the complexity of tobacco reinforcement and the importance of studying pharmacological and non-pharmacological non-nicotine factors

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But the tobacco companys chemical analyses also found that IQOS produced levels of 56 other constituents at higher concentrations than are found in cigarette smoke

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