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A non-metabolic function of hexokinase 2 in small cell lung cancer: promotes cancer cell stemness by increasing USP11-mediated CD133 stability

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Thus, the ACSL4LPCAT3 pathway functions as a key regulatory, integrating fatty acid metabolism with redox vulnerability

Furthermore, the accumulation of senescence-associated -galactosidase (SA--gal) due to increased lysosomal content indicates metabolic changes associated with aging 29

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The freed B12 then binds to intrinsic factor, a protein produced by gastric parietal cells, forming a complex that travels to the terminal ileum (the last section of the small intestine) where it is absorbed into the bloodstream