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The probe accurately visualizes tumors and metastases in mice, suggesting that it could be a convenient tool for fluorescence-guided cancer surgery (149)

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In deeply anaesthetised rats (placed in ventral position) the tail was transected with a surgical scalpel 3 cm from the tip (and submerged into a tube with 15 ml of saline at room temperature in vertical position) and the duration and amount of bleeding were measured to evaluate the hemostatic effect of the agents or saline administration

Eyes were then washed, dehydrated and embedded in paraffin wax

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However, despite this decrease, atazanavir levels still remain at high enough concentrations for the prevention of HIV virus replication