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doi: 10.1016/j.clinthera.2019.04.009 138 BuchwaldDAshleyRLPearlmanTKithPKomaroffAL

Thus, the appropriate control of NRF2 activity by KEAP1 is vital for maintaining HSCs under physiological conditions as well as their replenishment upon stress

Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines

Furthermore, glutathione in its reduced form (GSH) acts as a hydrogen donor in the detoxification process of hydrogen peroxide

These cultured AMD RPE were also more resistant to oxidation, suggesting that the oxidative environment of the diseased retina experienced in vivo stimulates the RPE to mount a compensatory response to minimize oxidative damage