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However, if used regularly at high doses, some NSAIDs can lead to gastrointestinal problems, kidney problems, and bleeding issues

This dysregulation orchestrates a symphony of cellular responses, including activation of oxidative stress, impairment of the ubiquitin-proteasome system and activation of protein toxicity stress responses, all of which converge to regulate cell death

This divergence demonstrates that while these tumors share a fundamental reliance on metabolic remodeling for survival, the specific molecular nodes they exploit are often cancer-typespecific, thereby presenting both common vulnerabilities and unique therapeutic opportunities

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Probiotics in aquaculture: a promising emerging alternative approach