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Oral LT4 is absorbed primarily in the small intestine, particularly in the jejunum and ileum, after dissolution in the stomach

It has been demonstrated to possess a wide range of anti-cancer properties, including anti-proliferative, pro-apoptotic, anti-angiogenic, and anti-metastatic effects

This assay is particularly useful for studying metabolic pathways and energy production processes

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Because of the risk of toxicity, patients with TPMT or NUDT15 deficiency require alternative therapy or dose modification (see DOSAGE AND ADMINISTRATION)