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The induction of GSH synthesis by nanomolar concentrations of NO in endothelial cells: a role of -glutamylcysteine synthetase and -glutamyltranspeptidase, FEBS Lett

In vitro, co-culture of GMSCs encapsulated in the 3D-collagen hydrogel with macrophages remarkably increased the secretion of IL-10, an anti-inflammatory cytokine characteristic of pro-regenerative (M2) macrophages, but robustly reduced LPS-stimulated secretion of TNF-1 and IL-1, two cytokines characteristic of pro-inflammatory (M1) macrophages

61: 438-453 e-ISSN 1732-2693 Honda Y, Kessoku T, Sumida Y, Kobayashi T, Kato T, Ogawa Y, Tomeno W, Imajo K, Fujita K, Yoneda M, Kataoka K, Taguri M, Yamanaka T, Seko Y, Tanaka S, Saito S, Ono M, Oeda S, Eguchi Y, Aoi W, Sato K, Itoh Y, Nakajima A

Additionally, the transcription of genes such as SAT1, HMOX1, and ACSL1, which sensitize cells to ferroptosis, were all increased by JQ1 [45,46,47] (Fig

Revising complex supramolecular polymerization under kinetic and thermodynamic control

11,62,796 Moreover, complex crosstalk between extrahepatic and intracellular pathways, as well as the presence of multiple isoforms of key metabolic enzymes, can limit the effectiveness of such treatments