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To assure strong reproducibility, to boost therapeutic benefit, and to lessen the possibility of harm, methodological improvements must be made to upcoming clinical studies using natural products for the treatment of PD

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The hormone has far greater timeframe to circulate around the body, bind to receptors, and exert its effects

Monitoring: Clinicians typically track melatonin rhythm, cortisol patterns, inflammatory markers (hs-CRP), and in some cases, telomere length via commercial testing as a baseline and follow-up tool

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